Symbol Name ID |
Lif
leukemia inhibitory factor MGI:96787 |
Darker colors indicate more annotations |
Mouse Phenotypes | abnormal osteoclast differentiation |
decreased T cell proliferation |
increased uterine NK cell number |
increased eosinophil cell number |
increased osteoclast cell number |
decreased leukocyte cell number |
abnormal macrophage morphology |
abnormal osteoclast morphology |
abnormal osteoclast physiology |
increased circulating interleukin-1 beta level |
increased circulating interleukin-6 level |
increased circulating tumor necrosis factor level |
increased circulating serum amyloid protein level |
decreased interleukin-10 secretion |
increased acute inflammation |
increased susceptibility to endotoxin shock |
increased susceptibility to bacterial infection induced morbidity/mortality |
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Availability | Mouse Genotype | |||||||||||||||||
Liftm1Cgre/Liftm1Cgre | ||||||||||||||||||
Liftm1Phb/Liftm1Phb | ||||||||||||||||||
Liftm1Stw/Liftm1Stw | ||||||||||||||||||
Liftm1Phb/Lif+ |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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