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Symbol
Name
ID
Lif
leukemia inhibitory factor
MGI:96787
Phenotype annotations related to immune system
Darker colors indicate more annotations

Mouse Phenotypes
abnormal osteoclast differentiation
decreased T cell proliferation
increased uterine NK cell number
increased eosinophil cell number
increased osteoclast cell number
decreased leukocyte cell number
abnormal macrophage morphology
abnormal osteoclast morphology
abnormal osteoclast physiology
increased circulating interleukin-1 beta level
increased circulating interleukin-6 level
increased circulating tumor necrosis factor level
increased circulating serum amyloid protein level
decreased interleukin-10 secretion
increased acute inflammation
increased susceptibility to endotoxin shock
increased susceptibility to bacterial infection induced morbidity/mortality
Availability Mouse Genotype
Liftm1Cgre/Liftm1Cgre
Liftm1Phb/Liftm1Phb
Liftm1Stw/Liftm1Stw
Liftm1Phb/Lif+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory